First hi-res images of active CRISPR enzyme will help improve genome editing

For the first time, scientists grappling with how to improve the efficiency of CRISPR technology — a gene-editing platform that uses an enzyme called Cas9 to precisely cut and edit specific sequences of DNA within a live cell — have captured atomic-level, three-dimensional images of the enzyme before and after cutting the DNA.
The images provide new structural information on how the enzyme works and will help researchers develop modified versions of the enzyme that can more efficiently and precisely alter targeted genes. The images and insights into Cas9 made from them are published in Nature Structural and Molecular Biology.

https://today.uic.edu/first-hi-res-images-of-active-crispr-enzyme-will-help-improve-genome-editing

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Press release from UBC: https://news.ubc.ca/2019/07/08/ubc-scientists-capture-images-of-gene-editing-enzymes-in-action/

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